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  • Title: [Role of erythrocyte membrane cholesterol in disorders of their structuro-functional status in patients with ischemic heart disease].
    Author: Liusov VA, Razumov VB, Redchits EG, Nemirovskiĭ LE, Savenkov MP.
    Journal: Kardiologiia; 1987 Jan; 27(1):86-8. PubMed ID: 3031356.
    Abstract:
    Increased molar cholesterol/phospholipid ratios, significantly increased membrane microviscosity, reduced filterability through a 3 micron-pore filter, increased aggregation and longer disaggregation time, and occasional abnormally large cells were found in erythrocyte assays of 80 coronary patients, as compared to normal subjects. It is suggested that erythrocyte microrheologic disorders are related to excessive cellular cholesterol content in coronary patients.
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