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  • Title: Identification of ACTH-producing intrathoracic tumors by measuring ACTH levels in aspirated specimens.
    Author: Doppman JL, Loughlin T, Miller DL, Pass HI, Chrousos GP, Cutler GB, Oldfield EH, Loriaux DL.
    Journal: Radiology; 1987 May; 163(2):501-3. PubMed ID: 3031729.
    Abstract:
    Three patients with Cushing syndrome secondary to ectopic adrenocorticotropic hormone (ACTH) production underwent direct 22-gauge needle aspiration of bronchial (two cases) and mediastinal (one case) carcinoid tumors. High levels of ACTH were measured in all three tumors. This technique permits absolute identification of an ectopic source of ACTH before surgery.
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