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  • Title: Characteristics, management, and outcomes of congenital biliary dilatation in neonates and early infants: a 20-year, single-institution study.
    Author: Urushihara N, Fukumoto K, Yamoto M, Miyake H, Takahashi T, Nomura A, Sekioka A, Yamada Y, Nakaya K.
    Journal: J Hepatobiliary Pancreat Sci; 2018 Dec; 25(12):544-549. PubMed ID: 30328288.
    Abstract:
    BACKGROUND: The aim of the present study was to investigate the characteristics, management, and outcomes of congenital biliary dilatation (CBD) in neonates and infants (<1 year old) in a single institution over the past 20 years. METHODS: From 1997 to 2016, 21 patients <1 year old underwent definitive surgery for CBD. Open surgery (OS) was performed between 1997 and 2008, and laparoscopic surgery (LS) has been performed since 2009. RESULTS: The bile duct showed cystic dilatation in all patients. Sixteen (76.2%) of the 21 patients were diagnosed prenatally, and the incidence increased with time (OS 63.6%, LS 90%). Fourteen patients (66.7%) were symptomatic before surgery, with jaundice in 11 (52.4%), acholic stool in seven (33.3%), and vomiting in three (14.3%). There were no significant differences in operation time and blood loss, but the postoperative fasting period and hospital stay were significantly shorter in the LS group (P < 0.05). There were no intraoperative complications, but there was one postoperative early complication in one LS group patient, who had bile leakage and was treated with redo hepaticojejunostomy. CONCLUSION: The incidences of prenatally diagnosed and asymptomatic patients increased with time. Although longer follow-up is needed, LS for CBD could be safely performed even in neonates and early infants.
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