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  • Title: Some properties of subunits of DNA gyrase from Pseudomonas aeruginosa PAO1 and its nalidixic acid-resistant mutant.
    Author: Inoue Y, Sato K, Fujii T, Hirai K, Inoue M, Iyobe S, Mitsuhashi S.
    Journal: J Bacteriol; 1987 May; 169(5):2322-5. PubMed ID: 3032915.
    Abstract:
    Subunits A and B of DNA gyrase were purified from Pseudomonas aeruginosa PAO1 and its mutant, which was resistant to nalidixic acid. Inhibition tests of DNA gyrases reconstituted with a combination of subunits from the two strains showed that an alteration of subunit A but not subunit B caused bacteria to resist fluoroquinolones.
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