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  • Title: Cluster growth adaptor for generation of bactericide Ag-Au bimetallic nanostructures: substantiation through spectral mapping data.
    Author: Ahmed HB.
    Journal: Int J Biol Macromol; 2019 Jan; 121():774-783. PubMed ID: 30336246.
    Abstract:
    Bimetallic nanostructures have emerged up as unique nano-objects due to the synergism between two metallic nanostructures. In the current approach, bactericide silver- gold bimetallic nanostructures have been fabricated using guar gum, which is employed as cluster growth adaptor. Silver‑gold bimetallic nanostructures were initially detected with the aid of UV-Visible spectrophotometer, where, the characteristic Surface Plasmon Resonance peak for bimetallic nanostructures was detected at 480-495 nm. Size controlling of nanostructures was achieved by interchanging the concentration of nano-metal precursors, their addition sequencing with strong alkali in reaction liquor, and temperature. According to transmission electron microscopic graphs and zetasizer data, silver‑gold bimetallic nanostructures are well-dispersed and spherical in shape. The as-mentioned tracking analyses confirmed that, the particle size for all the nanostructures were in range of 2.26 to 27.1 nm. All of the produced bimetallic nanostructures showed good stability with PdI ranged in 0.27-0.53. X-Ray diffraction analyses confirmed that, the manufactured bimetallic nanostructures were characterized by face cubic centered crystalline shape. According to FTIR, 1H NMR and 13C NMR spectral data, the mechanism of synthesis the as-required bimetallic nano-structures was elucidated and approved. The bactericidal action of the as-synthesized nanostructures is estimated to approve its compatibility to be applicable in various medical purposes.
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