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  • Title: Rapid diagnosis of herpes simplex virus infections in conventional and shell vial cell cultures using monoclonal antibodies.
    Author: Winter GF, Inglis JM, Cubie HA.
    Journal: J Virol Methods; 1987 Mar; 15(4):329-30. PubMed ID: 3034946.
    Abstract:
    One hundred specimens for herpes simplex virus (HSV) isolation were tested in parallel by conventional and by centrifugation-enhanced cell culture, followed by identification using monoclonal antibodies to HSV-1 and HSV-2. Sensitivity was comparable by the two methods; conventional culture was only marginally slower and was easier to fit into the routine of a busy laboratory. It is, therefore, advocated for HSV detection in clinical specimens.
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