These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Chronopharmacological Characteristics of the Effect of Hepatoprotectors in Experiment?
    Author: Bunyatyan ND, Kal'ko EA, Drogovoz SM, Kononenko AV.
    Journal: Bull Exp Biol Med; 2018 Oct; 165(6):754-757. PubMed ID: 30353338.
    Abstract:
    We studied circadian rhythms of activity of hepatoprotectors (Antral, Carsil, and glutargin) under conditions of acute paracetamol-induced hepatitis simulated in the morning, afternoon, evening, and at night (09.00, 15.00, 21.00, and 03.00). Antral and Carsil exhibited similar chronoprofiles with the maximum hepatoprotective activity at 09.00 and 21.00, while glutargin exhibited circadian pattern opposite and its activity was maximum at 15.00 and 03.00.
    [Abstract] [Full Text] [Related] [New Search]