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  • Title: D-galactosamine induced changes in rat liver plasma membranes lipid composition and some enzyme activities.
    Author: Petkova DH, Momchilova AB, Markovska TT, Koumanov KS.
    Journal: Int J Biochem; 1987; 19(3):289-91. PubMed ID: 3036613.
    Abstract:
    The influence of D-galactosamine administration on rat liver plasma membranes lipid composition, fluidity and some enzyme activities was investigated. D-Galactosamine was found to induce an increase of the total phospholipids, the cholesterol level and membrane rigidity. In liver plasma membranes of D-galactosamine-treated rats the exogenous phospholipase A2 activity was enhanced about 2 fold, whereas the endogenous activity was slightly decreased. No alteration of the neutral sphingomyelinase activity was observed.
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