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  • Title: The effect of dietary protein source and guar gum on gastrointestinal growth and enteroglucagon secretion in the rat.
    Author: Southon S, Gee JM, Johnson IT.
    Journal: Br J Nutr; 1987 Jul; 58(1):65-72. PubMed ID: 3040079.
    Abstract:
    1. Male Wistar rats (approximately 100 g) were given fibre-free semi-synthetic diets containing either casein or albumin (168 g/kg diet) as the protein source with or without guar gum (75 g/kg diet) (casein, albumin, casein guar gum and albumin-guar gum groups). 2. Small intestinal length, weights of caecal tissue and contents and plasma enteroglucagon concentration were significantly increased in guar-gum-fed animals compared with the fibre-free groups. 3. Total caecal weight and plasma enteroglucagon concentration were higher in the albumin-guar gum group compared with the casein-guar gum group. The weights of caecal tissue and contents were significantly increased in rats given the fibre-free albumin diet compared with those consuming a similar diet with casein as the protein source, although daily food intake tended to be lower. 4. It is concluded that the effect of materials classed as dietary fibre may be significantly influenced by the non-polysaccharide component of the diet, and that such interactions may influence both the growth and endocrine activity of the gastrointestinal tract.
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