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  • Title: [Anti-arrhythmic action of adenosine and the cyclic nucleotide content of the myocardium of rats with ischemia].
    Author: Eliseev VV, Poltavchenko GM, Evdokimova NR, Sokolova EN, Ovchinnikova AG.
    Journal: Biull Eksp Biol Med; 1987 Jul; 104(7):43-5. PubMed ID: 3040145.
    Abstract:
    In anesthetized rats a 30-min intravenous infusion of adenosine (2.5 mg/kg/min) performed after the coronary artery ligation significantly decreased the incidence and severity of early ischemic arrhythmias. After the infusion of adenosine, there was an increase in cGMP level in the left ventricular myocardium, cAMP content remained unchanged.
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