These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Participation of the nigro-striatal and mesolimbic dopaminergic systems of the brain in the control of components of learned motor reactions in the dog].
    Author: Shapovalova KB, Iakimovskiĭ AF.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1987 May; 73(5):579-89. PubMed ID: 3040479.
    Abstract:
    Microinjections of dopamine (3 micrograms) into the caudate nucleus head and into the nucleus accumbens produced unidirectional effects on the motor components of avoidance behaviour and posture adjustment in two groups of the dogs (intact ones and dogs with different degree of caudate pathology). However, each of these dopaminergic systems can regulate mainly certain components of motor program, i.e. nigrostriatal system--the initiation of both the conditioned postural adjustment and the voluntary movement and mesolimbic system--the degree of this movement manifestation in amplitude and stability of realization. The greatest effect was shown after combined microinjection of dopamine bilaterally into both structures in the dogs with akinetic form of caudate pathology. The obtained data suggest that the integration of the striatal and limbic dopaminergic mechanisms seems to be critical for initiation and control of components of voluntary movement in the dog.
    [Abstract] [Full Text] [Related] [New Search]