These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Erythroid-specific transcription of the chicken histone H5 gene is directed by a 3' enhancer.
    Author: Trainor CD, Stamler SJ, Engel JD.
    Journal: Nature; ; 328(6133):827-30. PubMed ID: 3041221.
    Abstract:
    The expression of a variety of vertebrate genes is transcriptionally regulated through tissue-specific cellular enhancer elements. An erythroid-specific enhancer sequence has recently been identified 3' to (downstream of) the chicken adult beta-globin gene. Here we report the identification of a second erythroid-specific enhancer sequence, which is 3' to the chicken histone H5 gene. The similarity of these two enhancer elements, with respect both to function and location relative to the target gene, implies some functional conservation in their evolution and in the mechanism by which they affect erythroid gene transcription.
    [Abstract] [Full Text] [Related] [New Search]