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  • Title: [A case of 2,8-dihydroxyadenine stones with a partial deficiency of adenine phosphoribosyltransferase].
    Author: Uejima S, Kataoka K, Uemura T, Tsujihashi H, Matsuura T, Kohri K.
    Journal: Hinyokika Kiyo; 1988 Apr; 34(4):656-60. PubMed ID: 3041775.
    Abstract:
    We report a case of 2, 8-dihydroxyadenine (2, 8-DHA) urolithiasis. A 39-year-old female was referred to our hospital with the complaint of right flank pain. An X-ray examination showed right hydronephrosis. On May 1986, right percutaneous nephrolithotripsy was performed. Infrared spectroanalysis revealed 2, 8-DHA and calcium phosphate mixed calculus. The adenine phosphoribosyltransferase activity in erythrocytes was partially deficient. Since the operation, 300 mg/day of allopurinol has been administered, and there have been no signs of recurrence.
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