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  • Title: [Mechanism of renal allograft rejection].
    Author: Michel F.
    Journal: Ann Urol (Paris); 1988; 22(3):161-7. PubMed ID: 3041909.
    Abstract:
    Renal allograft rejection, in an immunocompetent subject, résults from a cellular and humoral interaction. Lymphokines, which are immunity mediators (particularly interleukin 1 and 2, and gamma interferon) modulate these different cellular populations, among which T lymphocytes play a major role. The current knowledge of rejection mechanisms allows us to evaluate the principal targets of immunosuppressive drugs used to treat allograft rejection.
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