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  • Title: Relationship between current smoking, visual CT findings and emphysema index in cigarette smokers.
    Author: Jou SS, Yagihashi K, Zach JA, Lynch D, Suh YJ, COPDGene Investigators.
    Journal: Clin Imaging; 2019; 53():195-199. PubMed ID: 30419414.
    Abstract:
    PURPOSE: To evaluate whether visual CT findings could account for the effect of current smoking. METHODS: 500 CT scans were visually evaluated within each lobe. A multivariate model for emphysema index was constructed containing previously described confounders in addition to the visual components associated with smoking status. RESULTS: Current smokers displayed 23% less visual emphysema, 19% more airway wall thickening, and 188% more centrilogular nodule than former smokers (all p < 0.001). The effect of current smoking on the emphysema index decreased after adjustment with confounders and visual parameters. CONCLUSIONS: Visual CT findings could partially account for the effect of current smoking.
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