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  • Title: Molecular Analysis of Uropathogenic E.coli Isolates from Urinary Tract Infections.
    Author: Valadbeigi H, Esmaeeli E, Ghafourian S, Maleki A, Sadeghifard N.
    Journal: Infect Disord Drug Targets; 2019; 19(3):322-326. PubMed ID: 30421685.
    Abstract:
    INTRODUCTION: The aim of the current study was to investigate the prevalence of virulence genes in uropathogenic Escherichia coli (UPEC) isolates in Ilam. MATERIALS AND METHODS: For this purpose, a total of 80 UPEC isolates were collected for patients with UTIs during a 6 months period. The multiplex polymerase chain reaction (multiplex PCR) was used to detect the papEF, fimH, iucD, hlyA, fyuA, and ompT genes. RESULTS: The prevalence of fimH, papEF, iucD, fyuA, hlyA, hlyA, and ompT genes were 87.5%, 47.5%, 60%, 67.5%, 27.5%, 47.5% and 71.2%, respectively. Among all of the isolates, 27 profiles were obtained. CONCLUSION: Our findings demonstrated that the most prevalence was found for fimH, and different distribution of virulence genes suggested different ability of pathogenicity.
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