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  • Title: [Rickettsiaceae infections and fluoroquinolones].
    Author: Bertrand A, Janbon F, Jonquet O, Reynes J.
    Journal: Pathol Biol (Paris); 1988 May; 36(5):493-5. PubMed ID: 3043346.
    Abstract:
    Twenty nine patients with Rickettsiosis (Tick born fever, n: 22, Q fever, n: 7) has been treated with fluoroquinolones. These compounds was used alone n: 25 (Pefloxacin, n: 15; Ofloxacin, n: 10) or associated n: 4 (Pefloxacin + Rifampin). The general efficacy was excellent. Common Tick born fever and pulmonary forms of Q fever was fast cured. Severe Tick born fever (neurologic or polyvisceral forms, n: 5) and Q fever with long term hyperthermia, n: 4 cas always cured without complications but the time necessary to obtain apyrexia was often longer (6 cases).
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