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  • Title: Amphotericin B nephrotoxicity.
    Author: Raymond JR.
    Journal: Am Fam Physician; 1988 Aug; 38(2):199-203. PubMed ID: 3044056.
    Abstract:
    Nephrotoxicity becomes apparent days to months after the institution of amphotericin B therapy. It is characterized by azotemia, decreased renal plasma flow, decreased glomerular filtration rate, tubular defects, nephrocalcinosis, and diffuse, nonspecific histologic changes. Management consists of minimizing exposure to other nephrotoxins and ensuring adequate hydration.
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