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Title: Effects of various lengths of hypoglossal nerve resection on motoneuron survival. Author: Karasawa M, Yokouchi K, Kawagishi K, Moriizumi T, Fukushima N. Journal: J Clin Neurosci; 2019 Feb; 60():128-131. PubMed ID: 30446373. Abstract: We employed stereological analyses for whole quantification of hypoglossal (XII) motoneurons in adult rats that received varying degrees of resection of the XII nerve. Various lengths of nerve gaps (0.0-13.3 mm) were made at the main trunk of the unilateral XII nerve, and the total number of XII neurons on the injured and uninjured sides was counted 12 weeks after nerve resection. The stereologically estimated total number of XII neurons decreased after various lengths of nerve resection, and survival rates ranged from 34.4% to 87.1%. Statistically significant negative correlations were observed between increasing length of the resected nerve and decreasing XII neuron survival. It was concluded that the total number of XII neurons decreased after nerve resection and that survival rates of XII neurons were related to distances between resected nerve stamps.[Abstract] [Full Text] [Related] [New Search]