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  • Title: Reactivity of HLA typing sera against cultured lymphoblastoid cell lines and purified peripheral B and T cells from the same original donors.
    Author: Nakayama E, Itakura K.
    Journal: Jpn J Exp Med; 1977 Oct; 47(5):425-7. PubMed ID: 304500.
    Abstract:
    Anomalous cytotoxicity reactions are observed in some HLA typing sera when cultured lymphoid cells are used as targets. These extra reactions are also detected when the purified B cells from the original donors of the cell lines are used. This observation strongly indicates that these extra reactions are directed to the B cell alloantigens which are normally expressed on B cells of the original donor.
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