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  • Title: Previously unexplained HLA antigens of combined immunodeficiency disease due to Ia alloantigens.
    Author: Noreen HJ, van der Hagen BA, Greenberg LJ, Kersey J, Emme L, Yunis EJ.
    Journal: Transplant Proc; 1977 Dec; 9(4):1717-9. PubMed ID: 304619.
    Abstract:
    The presence of extra reactions in the HLA typing of a combined immunodeficiency patient may be attributed to B-cell alloantibodies in the HLA typing sera. The presence of these reactions can be used to identify HLA sera containing B-cell antibodies for further B-cell studies. The alloantibodies in this study have some association with the HLA-D determinants and segregate with HLA in normal families.
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