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  • Title: [ICO-13 monoclonal antibodies to the differentiation antigen of human hemopoietic cells].
    Author: Korotkova OV, Baryshnikov AIu, Tupitsyn NN, Dubinkin IV, Novikov AM.
    Journal: Biull Eksp Biol Med; 1988 Aug; 106(8):207-9. PubMed ID: 3046675.
    Abstract:
    Monoclonal antibodies (Mab) ICO-13 of IgM isotype reacted in indirect surface immunofluorescence test with 88.5 +/- 3.4% of thymocytes and 7.1 +/- 2.4% of T cells, but failed to react with other peripheral blood cells from healthy donors. The antigen disappeared in cells stored at 4 degrees C overnight or at -196 degrees C in liquid nitrogen. The antigen detected by Mab ICO-13 was expressed on blast cells of acute lymphoblast leukemias and lymphomas. The antigen was absent in chronic lymphoblast leukemia and blast crisis of chronic myeloid leukemia.
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