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  • Title: Oral absorption of cephalosporin antibiotics. 3. Synthesis and biological properties of 7 alpha-methoxy-7 beta-(arylacetamido)-3-chloro-3-cephem-4- carboxylic acids.
    Author: Pfeil-Doyle J, Kukolja S.
    Journal: J Med Chem; 1988 Oct; 31(10):1997-2000. PubMed ID: 3050090.
    Abstract:
    A series of 7 alpha-methoxy-7 beta-amido-3-chloro-3-cephem-4-carboxylic acids was prepared and evaluated for biological activity. When compared with the parent 7-non-methoxy analogues, these new 7 alpha-methoxy-3-chloro cephalosporins displayed diminished antimicrobial activity.
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