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  • Title: Clival Chondroid Chordoma: A Case Report and Review of the Literature.
    Author: Erazo IS, Galvis CF, Aguirre LE, Iglesias R, Abarca LC.
    Journal: Cureus; 2018 Sep 28; 10(9):e3381. PubMed ID: 30519520.
    Abstract:
    Chordomas are rare, slow-growing, and locally aggressive malignant neoplasms derived from primitive notochord remnants. The chondroid variety represents 14% of all chordomas mainly developing in the spheno-occipital region and presenting between the third and fifth decades of life. When developing intracranially, symptoms can range from headaches and neck pain to cranial nerve neuropathies and facial numbness. We illustrate a case of an adolescent woman who presented with excruciating facial pain, otalgia, decreased visual acuity, quadriparesis, headache, nausea, and dysphagia. Radiological studies revealed a large heterogeneous mass in the spheno-occipital region with clivus destruction. Biopsy and histopathology confirmed the diagnosis. Proper identification with prompt surgical resection and adjuvant radiotherapy remains critical to prevent complications.
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