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  • Title: [Effect of inhibitors and cations on the proteolytic activity of Bacillus mesentericus].
    Author: Imshenetskiĭ AA, Nesterova NG, Cherkesova GV, Fetisova ZS.
    Journal: Mikrobiologiia; 1988; 57(3):394-7. PubMed ID: 3054437.
    Abstract:
    The effect of some inhibitors and bivalent metal cations (Mn2+, Ca2+, Fe2+, Zn2+, Mg2+, Co2+ and Cu2+) on the proteolytic activity of two Bacillus mesentericus strains (strain 8 and strain 64 M-variant) was comparatively studied. The both enzymes were shown to be serine proteinases, but the proteinase of strain 64 was also a metal-dependent enzyme. Metal ions exerted no essential effect on the proteinase of strain 8. Ca2+ and Mg2+ ions stimulated the proteinase activity of strain 64 whereas Fe2+ and Zn2+ ions inhibited it in the case of three substrates. Therefore, the two proteinases are different.
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