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  • Title: THE ROLE OF RADIOACTIVE METHODS IN THE DIAGNOSTIC TYPE OF HYDRONEPHROSIS IN CLEAN-UP WORKERS OF CHORNOBYL ACCIDENT.
    Author: Korol PO, Tkachenko MM.
    Journal: Probl Radiac Med Radiobiol; 2018 Dec; 23():351-358. PubMed ID: 30582856.
    Abstract:
    RATIONALE: Since the introduction of radionuclide research methods into clinical practice, they occupy an importantplace in the diagnosis of hydronephrosis and, at the same time, sufficiently objective, sensitive and atraumaticmethods of investigation. OBJECTIVE: On the basis of retrospective data, to investigate the diagnostic role of radionuclide renography (RRG)and the method of indirect radionuclide renangiography (IRAG) in clean-up workers of Chornobyl accident withhydronephrosis. MATERIALS AND METHODS: A total of 257 patients with hydronephrosis (140 women and 117 men) aged 15 to 77 yearswere examined by the RRG and the IRAG. The RRG technique consists of intravenous administration of a solution of131I-hypurane (2.5 kBq/kg) and continuous registration for 20 minutes of the level of radioactivity above the kid-neys with the help of sensors of the renograph UR 1-1. The IRAG was conducted for 30-45 seconds with exposure1 frame per second after intravenous administration of a solution of 99mTc-pentatech (2 MBq/kg). RESULTS: The results of the radionuclide study of the hemodynamics of patients with different stages ofhydronephrosis made it possible to draw a conclusion regarding the expediency of taking into account the condi-tion of the cup-pelvic system in the preoperative period, as well as the parameters of the arterial and venous circu-lation. CONCLUSIONS: Combined use of X-ray and radionuclide methods allows establishing the cause and consequences ofhydronephrosis, to develop a rational treatment plan. RRG and IRAG are reliable methods of dynamic control in post-operative observation of clean-up workers of Chornobyl accident with hydronephrosis. Aktual'nist'. Z chasu vprovadzhennia v klinichnu praktyku radionuklidnykh metodiv doslidzhennia vony zaĭmaiut'odne z vazhlyvykh mists' v diagnostytsi gidronefrozu i ie dostatn'o ob’iektyvnymy, chutlyvymy ta atravmatychnymy me-todamy doslidzhennia.Meta: na pidstavi analizu retrospektyvnykh danykh doslidyty diagnostychnu rol' metodu radionuklidnoï reno-grafiï (RRG) ta nepriamoï radionuklidnoï renangiografiï (NRAG) v uchasnykiv likvidatsiï naslidkiv avariï na Chorno-byl's'kiĭ atomniĭ elektrostantsiï (ChAES), khvorykh na gidronefroz.Materialy ta metody. Metodom RRG ta NRAG obstezheno 257 patsiientiv na gidronefroz (140 zhinok ta 117 cho-lovikiv) vikom vid 15 do 77 rokiv. Metodyka RRG poliagaie u vnutrishn'ovennomu vvedenni rozchynu 131I-gipuranu(2,5 kBk/kg) ta bezperervniĭ reiestratsiï protiagom 20 khvylyn rivnia radioaktyvnosti nad nyrkamy za dopomogoiudatchykiv renografa UR 1-1. NRAG zdiĭsniuvaly na protiazi 30–45 sekund z ekspozytsiieiu 1 kadr za 1 sekundu pisliavnutrishn'ovennogo vvedennia rozchynu 99mTc-pentatekhu (2 MBk/kg).Rezul'taty. Rezul'taty radionuklidnogo vyvchennia gemodynamiky khvorykh z riznymy stadiiamy gidronefrozu do-zvolyly zrobyty vysnovok stosovno dotsil'nosti (neobkhidnosti) vrakhuvannia v peredoperatsiĭnomu periodi iakstanu chashkovo-myskovoï systemy urazhenoï nyrky, tak i pokaznykiv arterial'nogo ta venoznogo krovoobigu.Vysnovky. Kombinovane zastosuvannia rentgenoradionuklidnykh metodiv dozvoliaie vstanovyty prychynu tanaslidky gidronefrozu, rozrobyty ratsional'nyĭ plan likuvannia. RRG ta NRAG, ie nadiĭnymy metodamy dynamichno-go kontroliu v pisliaoperatsiĭnomu sposterezhenni za uchasnykamy likvidatsiï naslidkiv avariï na ChAES, khvorymy nagidronefroz.
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