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  • Title: Clinical survey of adverse reactions to contrast media.
    Author: Katayama H, Tanaka T.
    Journal: Invest Radiol; 1988 Sep; 23 Suppl 1():S88-9. PubMed ID: 3058637.
    Abstract:
    From October 1983 to June 1986, 33,400 individuals participated in a clinical survey of adverse reactions to conventional high osmolar contrast media. The frequency of reactions was 7.5% (2,523/33,400). No fatal cases resulted. In patients pretesting positive, the incidence of adverse reactions was 48%. In individuals with a positive history of allergy, the incidence of the reactions was 52%. There was no correlation between the incidence of reactions and the presence or absence of a history of previous contrast media administration. The value of pretesting can not be negated from the present results.
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