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  • Title: [A Case of Mixed Adenoneuroendocrine Carcinoma(MANEC)of the Duodenum with Rapid Liver Metastases after Pancreatoduodenectomy].
    Author: Maeda Y, Nakahara O, Tamaoki Y, Saito S, Hasuta S, Nasu J, Baba H.
    Journal: Gan To Kagaku Ryoho; 2018 Dec; 45(12):1747-1750. PubMed ID: 30587733.
    Abstract:
    A 62-year-old man presented at our hospitalwith generalfatigue and tarry stool. Gastrointestinalendoscopy revealed a tumor in the first portion of the duodenum. Histologically, biopsy specimens indicated adenocarcinoma, and a subtotal stomach- preserving pancreatoduodenectomy was performed. The finalhistol ogicaldiagnosis was mixed adenoneuroendocrine carcinoma(MANEC)of the duodenum. Liver metastases appeared rapidly within 3 months after surgery. We report on the management of a rare case of MANEC in the duodenum.
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