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  • Title: Comparison of 5-aminosalicylic acid (3 g) and prednisolone phosphate sodium enemas (30 mg) in the treatment of distal ulcerative colitis. A prospective, randomized, double-blind trial.
    Author: Mulder CJ, Tytgat GN, Wiltink EH, Houthoff HJ.
    Journal: Scand J Gastroenterol; 1988 Oct; 23(8):1005-8. PubMed ID: 3059450.
    Abstract:
    Twenty-nine patients with attacks of distal ulcerative colitis were treated randomly with 3 g 5-aminosalicylic acid (5-ASA) or 30 mg of prednisolone phosphate sodium (PP) enemas (40 ml). Endoscopic, clinical, and histologic improvement were comparable in the two treatment groups. Our study showed that topical treatment with 5-ASA is as efficacious as PP in improving distal ulcerative colitis.
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