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  • Title: Normal and dystrophin-deficient muscle fibers in carriers of the gene for Duchenne muscular dystrophy.
    Author: Bonilla E, Schmidt B, Samitt CE, Miranda AF, Hays AP, de Oliveira AB, Chang HW, Servidei S, Ricci E, Younger DS.
    Journal: Am J Pathol; 1988 Dec; 133(3):440-5. PubMed ID: 3059802.
    Abstract:
    Dystrophin is the gene product that is affected in Duchenne muscular dystrophy (DMD). Antibodies against dystrophin were used to study the protein in muscle fibers of carriers of the gene. The results showed that DMD carriers have normal and dystrophin-deficient fibers. Dystrophin immunohistochemistry may be helpful for the detection of DMD carriers.
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