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  • Title: [A single evening dose of 300 mg ranitidine in the treatment of acute attacks of gastric and duodenal ulcers. Evaluation of 1,208 patients].
    Author: Bories P, Tournade JM, Alberola B, Pappo M.
    Journal: Ann Gastroenterol Hepatol (Paris); 1988 Oct; 24(5):227-32. PubMed ID: 3061358.
    Abstract:
    The aim of this study was to evaluate, on a wide population of outpatients, the efficacy of ranitidine 300 mg given once a day at bedtime in duodenal and gastric ulcer. Healing rates observed on 1,208 patients were 85.2% (703/825) in duodenal ulcer, 79.5% (268/337) in gastric ulcer and 71.7% (33/46) in double localization, duodenal and gastric. Analysis of predictive factors of treatment failure showed no influence of smoking on the efficacy of ranitidine neither in duodenal nor gastric ulcer.
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