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  • Title: Computed Tomography of Lobular Dissecting Hepatitis in a Young Golden Retriever.
    Author: Hostnik ET, Parker VJ, Cullen JM.
    Journal: J Am Anim Hosp Assoc; 2019; 55(2):e55203. PubMed ID: 30653361.
    Abstract:
    A 9 mo old female intact golden retriever presented for evaluation of chronic lethargy and decreased appetite. The serum biochemistry profile revealed increased liver enzymes consistent with a mixed hepatocellular and cholestatic pattern. A multiphase computed tomography angiography was performed to evaluate for a portosystemic shunt. Numerous hyperattenuating nodules were identified throughout the liver on the noncontrast-enhanced series. Histologic evaluation of percutaneous needle biopsy samples of a liver nodule showed a rare form of hepatitis called lobular dissecting hepatitis. Lobular dissecting hepatitis should be considered as a differential in young dogs with precontrast hyperattenuating hepatic nodules on noncontrast-enhanced computed tomography.
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