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  • Title: A simple electrical approach to monitor dielectrophoretic focusing of particles flowing in a microchannel.
    Author: Reale R, De Ninno A, Businaro L, Bisegna P, Caselli F.
    Journal: Electrophoresis; 2019 May; 40(10):1400-1407. PubMed ID: 30661234.
    Abstract:
    This paper reports an impedance-based system for the quantitative assessment of dielectrophoretic (DEP) focusing of single particles flowing in a microchannel. Particle lateral positions are detected in two electrical sensing zones placed before and after a DEP-focusing region, respectively. In each sensing zone, particle lateral positions are estimated using the unbalance between the opposite pulses of a differential current signal obtained with a straightforward coplanar electrode configuration. The system is used to monitor the focusing of polystyrene beads of 7 or 10 μm diameter, under various conditions of DEP field intensities and flow rates that produce different degrees of focusing. This electrical approach represents a simple and valuable alternative to optical methods for monitoring of particle focusing systems.
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