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  • Title: Iridoid, phenylethanoid and flavonoid glycosides from Forsythia suspensa.
    Author: Wei Q, Zhang R, Wang Q, Yan XJ, Yu QW, Yan FX, Li C, Pei YH.
    Journal: Nat Prod Res; 2020 May; 34(9):1320-1325. PubMed ID: 30676780.
    Abstract:
    As part of our continuing efforts to explore bioactive compounds from natural resources, a new iridoid glycoside, adoxosidic acid-6'-oleuroperic ester (1), together with one known phenylethanoid glycoside (2) and two known flavonoid glycosides (3-4) were isolated from the fruit of Forsythia suspensa. The structure of the new compound (1) was elucidated through 1D and 2D NMR spectroscopic data and HR-ESIMS. Interestingly, compound 1 was a monoterpene ester of one iridoid glycoside. Compounds 2-4 were identified as calceolarioside A (2), kaempferol-3-O-rutinoside (3), kampferol-3-O-robinobioside (4) on the basis of NMR spectroscopic data analyses and comparison with the data reported in the literature. The antiviral activity aganisist influenza A (H5N1) virus of compound 1 was studied as well.
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