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  • Title: [Advances in the research of transcatheter arterial thrombolysis for severe frostbite therapy].
    Author: Zhang JL, Fu JX, Yuan K, Yuan B, Wang MQ.
    Journal: Zhonghua Shao Shang Za Zhi; 2019 Jan 20; 35(1):74-76. PubMed ID: 30678407.
    Abstract:
    Severe frostbite (grade Ⅲ to Ⅳ) is a common disease accompanied with high disability rate in cold regions, especially for military training and disaster events in cold regions. The treatment of severe frostbite mainly includes rapid rewarming in the early stage and amputation in the later stage; while the damage of vascular endothelial cells, microvascular thrombosis, and decreased tissue perfusion secondary to severe frostbite are important factors affecting prognosis. Transcatheter arterial thrombolysis is a new technique for the treatment of severe frostbite. It has the advantages of minimally invasive, high safety, and significantly reduced amputation rate. We reviewed the advances in the research of transcatheter arterial thrombolysis for the treatment of severe frostbite. 严重(Ⅲ~Ⅳ度)冻伤是寒区较常见病，尤其多见于寒区军事作业及灾害事件，且致残率较高。严重冻伤的治疗方法主要包括前期的快速复温以及后期的截肢治疗，而严重冻伤继发的血管内皮细胞损伤、微血管内血栓形成、组织灌注减少是影响预后的重要因素。经导管动脉溶栓是治疗严重冻伤的新技术，具有微创、安全性高、可显著降低截肢率等优势，本文对此方面的研究进展进行综述。.
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