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  • Title: Splanchnic glucose balance and insulin resistance in the early postoperative phase of cardiac surgery.
    Author: Nilsson F, Ekroth R, Milocco I, Nilsson NJ, Svensson S, Berglin E, William-Olsson G.
    Journal: JPEN J Parenter Enteral Nutr; 1988; 12(6):574-8. PubMed ID: 3068375.
    Abstract:
    The splanchnic balance of glucose was studied in the basal state and at three levels of "clamped" hyperinsulinemia (260 +/- 23, 510 +/- 59, 3875 +/- 367 mU/liter) in 24 patients (43-70 years of age), who had undergone coronary surgery about 1 hr previously. The splanchnic balance of glucose in the basal state was negative in all patients (-1.6 +/- 0.3 mg/kg/min) and was changed into a zero-balance within 30 min when 0.15 or 0.3 U/kg/hr of insulin was infused. At an insulin infusion rate of 1.0 U/kg/hr the net splanchnic glucose balance was turned into a significant positive balance of an average 0.9 +/- 0.3 mg/kg/min.
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