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  • Title: [Genetic determinants of antibiotic resistance in gram negative bacteria].
    Author: Anisimova LA, Boronin AM.
    Journal: Mol Gen Mikrobiol Virusol; 1988 Nov; (11):3-12. PubMed ID: 3070380.
    Abstract:
    Modern data on spreading, structural and functional organization and evolution of the genetic determinants of antibiotic resistance in the gram-negative bacteria are reviewed. Some mechanisms for resistance to trimethoprime, sulphonamides, tetracyclines, chloramphenicol aminoglycosides, beta-lactam antibiotics controlled by the plasmid and chromosomal genes are presented. The problem of using the molecular DNA-probes containing the genetical determinants for antibiotic resistance in the practical work of clinical laboratories is discussed.
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