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  • Title: [Treatment of vasospasm in aneurysmal meningeal hemorrhage using intravenous nimodipine. Multicenter cooperative study].
    Author: Frerebeau P, Janny P, Taquoi G, Besson G, Buchheit F, Childs M, Houtteville JP, Jan M, Jomin M, Pecker J.
    Journal: Neurochirurgie; 1988; 34(6):383-8. PubMed ID: 3070420.
    Abstract:
    We present a multicentric randomized double-blind study of the curative effect of intravenous Nimodipine on the post hemorrhagic vasospasm after aneurysmal rupture. On 122 validated cases out of 188 analyzed patients, the study demonstrates a significative effect on the mortality and severe morbidity related to vasospasm: the reduction of the risk is appreciated to 72%. The major effect is obtained on the mortality risk. A selective effect can be demonstrate on the isolated vasospasm.
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