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  • Title: [Antibiotic therapy of infected cerebrospinal fluid in hydrocephalus treated by a shunt].
    Author: Isla Guerrero A, Peña García P, Ortega V, Alvarez Ruiz F, Moriche Carretero M, Paredes García E, García Blázquez M.
    Journal: An Esp Pediatr; 1988 Dec; 29(6):435-9. PubMed ID: 3072889.
    Abstract:
    Nine hydrocephalic shunted children with infected cerebrospinal fluid (CSF) were treated. Ages ranged from 0 to 10 years. Diagnosis was made through clinical symptoms, CSF examination, echographic and computed tomography (CT). The microorganism which was seen more frequently, was S. epidermidis. This germ was more often found in young children. Treatment of these patients consisted of a systematic change of the shunt which was externally diverted, implantation of a CSF Ommaya reservoir in the lateral ventricle, and intraventricular and systemic administration of antibiotic, were made. Using this protocol CSF sterilization was obtained in all cases, after 5 to 12 days of treatment. CSF shunt infected with S. epidermidis can be effectively cleaned with daily intra-shunt vancomycin, and shunt infected with gram-negative are also cleaned with daily intra-shunt gentamycin.
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