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  • Title: Somatostatin reduces the release of colony-stimulating activity (CSA) from PHA-activated mouse spleen lymphocytes.
    Author: Hinterberger W, Cerny C, Kinast H, Pointner H, Tragl KH.
    Journal: Experientia; 1978 Jul 15; 34(7):860-2. PubMed ID: 307497.
    Abstract:
    PHA-activated lymphocytes release colony-stimulating activity (CSA) for macrophage-granulocyte precursor cells (colony forming units, CFUc) in the culture medium. Somatostatin, known to interfer with ribosomal protein synthesis, was demonstrated to reduce the release of CSA from PHA-treated mouse spleen lymphocytes.
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