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Title: Drugs and psychological treatments for agoraphobia/panic and obsessive-compulsive disorders: a review. Author: Marks I, O'Sullivan G. Journal: Br J Psychiatry; 1988 Nov; 153():650-8. PubMed ID: 3076498. Abstract: In the short term, both antidepressants and exposure therapy usually improve agoraphobia/panic (AP) and obsessive-compulsive (OC) disorders and are accepted by most patients; psychological methods omitting exposure are not consistently helpful. Antidepressants have a broad-spectrum rather than specific anti-agoraphobia/panic or anti-obsessive-compulsive action. For long-term efficacy, there is good evidence for the value of exposure, but none for drugs. Because of relapse on ceasing drugs, and their side-effects, medication is less useful as the first line of treatment for chronic agoraphobia/panic or obsessive-compulsive disorder than is the lastingly helpful approach of exposure. Antidepressants are worth trying when patients refuse or fail with exposure therapy, or are dysphoric.[Abstract] [Full Text] [Related] [New Search]