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  • Title: [Rendu-Osler disease and recurrent thromboembolic venous disease].
    Author: Ben Salah R, Frikha F, Chebbi D, Chabchoub I, Bahloul Z.
    Journal: J Med Vasc; 2019 Feb; 44(1):76-78. PubMed ID: 30770085.
    Abstract:
    Rendu-Osler-Weber syndrome is a rare systemic fibrovascular dysplasia, recognized by mucocutaneous telangiectasias, arteriovenous malformations, epistaxis and family history. Venous thromboembolic disease is a poor prognostic factor in this disease given the risk of increased bleeding caused by anticoagulant therapy. We report a new case of a 56-year-old patient with Osler disease who developed recurrent thromboembolic venous disease when anticoagulants were discontinued. According to a review of the literature, this association does not appear to be fortuitous and is a factor of disease severity.
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