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  • Title: [Effect of vasopressin on the lower esophageal sphincter. Study on the action mechanism of vasopressin in bleeding esophageal varices].
    Author: Häuptle B, Güller R.
    Journal: Schweiz Med Wochenschr; 1978 Jul 15; 108(28):1087-8. PubMed ID: 307814.
    Abstract:
    The effect of vasopressin on the lower esophageal sphincter has been investigated in 12 healthy volunteers. Peripheral infusion of 0.2 U/min resulted in a significant (p less than 0.05) decrease in sphincter pressure. Accordingly, vasopressin-induced myogenic compression of bleeding varices has been ruled out as a potential additional hemostatic mechanism of vasopressin.
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