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  • Title: Biological activities of interleukins and colony-stimulating factors.
    Author: Kitagawa S, Saito M.
    Journal: Tokai J Exp Clin Med; 1988 Dec; 13(6):307-11. PubMed ID: 3078752.
    Abstract:
    The complementary DNAs encoding interleukins (interleukins 1, 2, 3, 4, 5 and 6) and colony-stimulating factors (granulocyte-macrophage, granulocyte, and macrophage colony-stimulating factors) have been cloned. These DNA clones have allowed the large-scale production of recombinant forms of these cytokines and the extensive studies of their biological activities. These advances have led to a much better understanding of the role of these cytokines in regulation of immune responses and hematopoiesis, and have clarified that these cytokines have multiple effects on various types of cells.
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