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  • Title: Dual-grid mesh-based Monte Carlo algorithm for efficient photon transport simulations in complex three-dimensional media.
    Author: Yan S, Tran AP, Fang Q.
    Journal: J Biomed Opt; 2019 Feb; 24(2):1-4. PubMed ID: 30788914.
    Abstract:
    The mesh-based Monte Carlo (MMC) method is an efficient algorithm to model light propagation inside tissues with complex boundaries, but choosing appropriate mesh density can be challenging. A fine mesh improves the spatial resolution of the output but requires more computation. We propose an improved MMC-dual-grid mesh-based Monte Carlo (DMMC)-to accelerate photon simulations using a coarsely tessellated tetrahedral mesh for ray-tracing computation and an independent voxelated grid for output data storage. The decoupling between ray-tracing and data storage grids allows us to simultaneously achieve faster simulations and improved output spatial accuracy. Furthermore, we developed an optimized ray-tracing technique to eliminate unnecessary ray-tetrahedron intersection tests in optically thick mesh elements. We validate the proposed algorithms using a complex heterogeneous domain and compare the solutions with those from MMC and voxel-based Monte Carlo. We found that DMMC with an unrefined constrained Delaunay tessellation of the boundary nodes yielded the highest speedup, ranging from 1.3  ×   to 2.9  ×   for various scattering settings, with nearly no loss in accuracy. In addition, the optimized ray-tracing technique offers excellent acceleration in high-scattering media, reducing the ray-tetrahedron test count by over 100-fold. Our DMMC software can be downloaded at http://mcx.space/mmc.
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