These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Reassortments among Avian Influenza A(H5N1) Viruses Circulating in Indonesia, 2015-2016.
    Author: Karo-Karo D, Bodewes R, Wibawa H, Artika M, Pribadi ES, Diyantoro D, Pratomo W, Sugama A, Hendrayani N, Indasari I, Wibowo MH, Muljono DH, Stegeman JA, Koch G.
    Journal: Emerg Infect Dis; 2019 Mar; 25(3):465-472. PubMed ID: 30789142.
    Abstract:
    Highly pathogenic avian influenza (HPAI) A(H5N1) viruses have been circulating since 2003 in Indonesia, with major impacts on poultry health, severe economic losses, and 168 fatal laboratory-confirmed human cases. We performed phylogenetic analysis on 39 full-genome H5N1 virus samples collected during outbreaks among poultry in 2015-2016 in West Java and compared them with recently published sequences from Indonesia. Phylogenetic analysis revealed that the hemagglutinin gene of all samples belonged to 2 genetic groups in clade 2.3.2.1c. We also observed these groups for the neuraminidase, nucleoprotein, polymerase, and polymerase basic 1 genes. Matrix, nonstructural protein, and polymerase basic 2 genes of some HPAI were most closely related to clade 2.1.3 instead of clade 2.3.2.1c, and a polymerase basic 2 gene was most closely related to Eurasian low pathogenicity avian influenza. Our results detected a total of 13 reassortment types among HPAI in Indonesia, mostly in backyard chickens in Indramayu.
    [Abstract] [Full Text] [Related] [New Search]