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  • Title: Cigarette smoking-induced acute eosinophilic pneumonia: A case report.
    Author: Liu X, Sun W, Meng W, Xiao Y, Feng G, Shi B.
    Journal: Medicine (Baltimore); 2019 Mar; 98(9):e14704. PubMed ID: 30817609.
    Abstract:
    RATIONALE: Acute eosinophilic pneumonia (AEP) is a rare pulmonary disease, which is characterized by diffuse pulmonary eosinophilia. The pathogenesis remains unknown. Here we report a patient with AEP following a recently acquired habit of smoking. PATIENT CONCERNS: A 21-year-old female presented with fever, dry cough, and acute hypoxic respiratory distress for 2 days. Chest computed tomography showed bilateral ground glass opacities, patchy nodules, and pleural effusions. Blood tests showed a gradually raised peripheral eosinophils level. DIAGNOSES: Bronchoalveolar lavage fluid revealed marked elevation of eosinophils. She was diagnosed with AEP. INTERVENTIONS: Systemic methylprednisolone was immediately used for treatment. OUTCOMES: Her clinical symptoms and chest radiographs improved promptly after treatment. LESSONS: Cigarette smoking might be an underlying triggering factor of AEP. Diffuse alveolar infiltrates and a gradually increasing peripheral eosinophilia should raise the concern especially in recent smoking patients.
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