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  • Title: Magnetic resonance demonstration of normal CSF flow.
    Author: Sherman JL, Citrin CM.
    Journal: AJNR Am J Neuroradiol; 1986; 7(1):3-6. PubMed ID: 3082142.
    Abstract:
    The magnetic resonance (MR) imaging appearance and incidence of flowing cerebrospinal fluid (CSF) in the brain were investigated. The MR scans of 46 randomly selected patients with normal examinations were retrospectively reviewed. All patients were studied using both T2-weighted and T1-weighted spin-echo pulse sequences. Thirty-one patients (67%) had decreased intensity in the aqueduct of Sylvius on the T2-weighted images when compared with the intensity of CSF in the lateral ventricles. This was termed the CSF flow-void sign. The feature was present in the caudal fourth ventricle in 15 patients (32%) and in the third ventricle in two patients (4%) on T2-weighted scans. It was seen in only 13% of patients on T1-weighted scans. It is believed the CSF flow-void sign represents pulsatile CSF flow. Its recognition is important because it explains the inhomogeneity in the appearance of the CSF, which could be confused with pathologic processes. It may be valuable in the routine evaluation of MR examinations if it does reflect CSF circulatory dynamics.
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