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  • Title: AGE SPECIFIC CORRELATION PECULIARITIES OF THE DIAMETER AND DEFORMATION OF A HEALTHY HUMAN ERYTHROCYTE MEMBRANE.
    Author: Khetsuriani R, Topuria D, Pruidze N, Gognadze T, Durglishvili N, Amiranashvili I.
    Journal: Georgian Med News; 2019 Jan; (286):132-135. PubMed ID: 30829605.
    Abstract:
    The purpose of our research was to determine the interrelation peculiarities of erythrocyte membrane deformability and cell diameter in a practically healthy person, in different age groups. 60 volunteers were selected for this survey in 5 age groups: 1) 17-25, 2) 25-35, 3) 35-60, 4) 60-75, 5) 75-90. As a result of the study, it was determined that with aging the diameter of peripheral blood erythrocytes increases and an indicator of deformability, in contrary, decreases. The average diameter of erythrocytes in young people, is directly correlated with erythrocyte deformability, while in elderly people, negative correlation is revealed between erythrocytes diameter and their deformability. Decrease in membrane deformability, demonstrated in peripheral blood erythrocytes of elderly people, indicates the participation of different mechanisms in erythrocyte membrane deformity regulation, it might be related to age-related metabolic changes.
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