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  • Title: Beta-lactamase-producing isolates of Neisseria gonorrhoeae in Cape Town.
    Author: Simpson JA, Oliver SP.
    Journal: S Afr Med J; 1986 Mar 01; 69(5):307-8. PubMed ID: 3083514.
    Abstract:
    Isolates of Neisseria gonorrhoeae from patients attending the sexually transmitted disease clinics of the Cape Town Municipal Health Department were examined for beta-lactamase (penicillinase) production by a chromogenic cephalosporin test. Of the 208 isolates, 4 (less than 2%) produced beta-lactamase. When grown on chocolate blood agar plates 3 isolates showed no inhibition of growth around a penicillin disc; the 4th had a markedly reduced zone of inhibition. The minimum inhibitory concentrations of penicillin for these 4 strains were from 1 to 4 micrograms/ml.
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